Southern Region Vacations & Trips from $2,856

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Photo by Kalunde Mbevi

Your Southern Region Vacation

When adventure calls, answer it with a tailor-made vacation package to Southern Region. Wherever it is you're headed and whatever you have planned, prepare to discover a destination that'll make you truly feel alive. Your trip to Southern Region wouldn't be complete without spending some time in its best cities, starting with Blantyre. A couple of the top attractions here include Mandala House and Carlsberg Brewery. Zomba is another favorite city with Southern Region travelers. Visitors to this city enjoy Emperor's View and Williams Falls. Expedia has everything you need when it comes to organizing your Southern Region vacation. From flights and hotels, to activities and more, we know how to create a travel experience like no other.

Top destinations in Southern Region

The Latest Southern Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Malawi Sun Hotel & Conference Centre
Crossroads Hotel Blantyre
Amaryllis Hotel
Golden Peacock Hotel Blantyre
Sunbird Waterfront

Find the Best Southern Region Vacation Packages

Southern Region Essential Information

Language
Chichewa
Currency
Malawian kwachas
Closest Airport
Chileka Intl. Airport (BLZ)
Top Sights
Lake Malawi National Park, Monkey Bay Beach and Liwonde National Park

Southern Region Hotel Deals

Protea Hotel by Marriott Blantyre Ryalls

Protea Hotel by Marriott Blantyre Ryalls

4.5 out of 5
2 Hannover Avenue Blantyre
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $173 total per night from Jun 5 to Jun 6
$173 total
Jun 5 - Jun 6
Total with taxes and fees
8.8/10 Excellent! (149 reviews)
"Everything about this hotel is great except for internet connectivity. It is not the best for business travel where you are likely to have virtually meetings while at the hotel. IT is very helpful in providing an individual router upon request which is an improvement but does not always provide uninterrupted ..."

Reviewed on Mar 30, 2026

Protea Hotel by Marriott Blantyre Ryalls
Amaryllis Hotel

Amaryllis Hotel

5 out of 5
2 Laws Rd Blantyre Southern Region
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $173 total per night from May 28 to May 29
$173 total
May 28 - May 29
Total with taxes and fees
7.2/10 Good! (5 reviews)
"Average plus"

Reviewed on May 20, 2026

Amaryllis Hotel
Casa Mia

Casa Mia

3 out of 5
Kabula Hill Road Blantyre
$96 nightly
The price is $115 total per night from Jun 10 to Jun 11
$115 total
Jun 10 - Jun 11
Total with taxes and fees
8.6/10 Excellent! (127 reviews)
"The room was basic, but clean and comfortable. The mosquito net was in great condition. The restaurant steak is delicious, and the included breakfast (and espresso machine!) was excellent. My only gripe is that the staff seemed not to understand how things worked -- every question I asked had to ..."

Reviewed on Apr 14, 2026

Casa Mia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southern Region

What to do in Southern Region

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.